Side effect of diclofenac in pregnancy

7. Serious side effects of Flector Patch difficult breathing, swelling in your face or throat, skin pain, red or purple skin rash with blistering and peeling, chest pain spreading to your jaw or shoulder, sudden numbness or weakness, slurred speech, leg Stop using diclofenac and get medical help right away if you notice any of the following rare but very serious side effects: stomach/abdominal pain that doesn't go away, black/bloody stools, vomit Dec 26, 2023 · Shortness of breath, a big weight gain, or swelling in the arms or legs. Hematologic Jan 29, 2024 · Background Breastfeeding is considered to be the most effective way of ensuring the health and survival of newborns. com. Most publications have evaluated the safety of NSAIDs on pregnancy outcome as a group of substances. sensation of spinning. Diarrhea and abdominal pain may resolve after 2-7 days. It comes in different formulations, including tablets, gels, and topical solutions. Dec 12, 2022 · Most of the time, this reaction has signs like fever, rash, or swollen glands with problems in body organs like the liver, kidney, blood, heart, muscles and joints, or lungs. If your symptoms become worse, check with your doctor. 85mg) potassium per 50mg tablet. 8 mg of diclofenac). This medicine is for use on the hands, wrists, elbows, knees, ankles, or feet. Even though diclofenac has a relatively high selectivity for the cyclooxygenase-2 (COX-2) enzyme, 70% of COX-1, the enzyme associated with platelet aggregation, is also inhibited at therapeutic levels of the liver problems --nausea, diarrhea, stomach pain (upper right side), tiredness, itching, dark urine, jaundice (yellowing of the skin or eyes); or. Side-effects, further information. These problems can happen without warning signs. Most of these side effects do not require medical attention and resolve with time. Diclofenac shows side effects like nausea, headache, stomach pain, and diarrhoea. Do not use this medicine (diclofenac delayed-release tablets) right before or after bypass heart surgery. Serious side effects of Pennsaid include risk of serious cardiovascular (heart attack, stroke) and gastrointestinal events (bleeding, ulceration, and perforation Jun 1, 2024 · The goal of the present study was to observe how diclofenac sodium affects the development of chick embryos. Contact your doctor right away if you experience loosening of skin, white or red skin discolorations, yellowing of the skin and eyes, itching, or flushing. Pregnancy & Breastfeeding Can I take Capsaicin And Diclofenac (Dermacinrx Lexitral Pharmapak) if I’m pregnant or breastfeeding? Common side effects of diclofenac topical may include: skin redness, numbness or tingly feeling, itching, dryness, scaling, or peeling where the medicine was applied. If you have questions, talk with the doctor. Applies to diclofenac/fluorouracil topical: topical cream. 92mg) potassium per 25mg tablet and 0. This information from Lexicomp explains what you need to know about this medication, including what it’s used for, how to take it, its side effects, and when to call your healthcare provider. Known adverse effects of NSAIDs in late pregnancy are premature constriction of the fetal ductus arteriosus (e. If you are pregnant, you should not take diclofenac unless your doctor tells you to. If you experience any of the following signs of allergy, STOP using Diclofenac Gel and tell a doctor or pharmacist immediately: Oct 18, 2023 · low red blood cells (anemia)--pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet. 3, with a power of 80%. See also: Side effects (in more detail) Diclofenac dosing information Usual Adult Dose for Osteoarthritis: Diclofenac: 50 mg orally 2 to 3 times a day or 75 mg orally Sep 30, 2020 · Description for Dyloject. flatulence. hot and dry skin. pain with swallowing. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Constipation, diarrhea, stomach pain, upset stomach, or throwing up Apr 15, 2024 · The risk can happen within the first weeks of using this medicine (diclofenac delayed-release tablets) and may be greater with higher doses or long-term use. Stroke: tiredness, lightheadedness, blurred vision, difficulty speaking, difficulty walking, weakness on one side of the body. Acetaminophen and diclofenac sodium are widely prescribed analgesics for postpartum pain relief, but there have been few recent reports on the mammary transfer of Sep 8, 2021 · Dynapar Tablet is a combination of Diclofenac and Paracetamol. These effects can be deadly. Magnesium containing antacids worsen diarrhea caused by misoprostol. Nov 8, 2022 · Patients who take diclofenac may experience stomach problems as a common side effect—this may include indigestion, stomach pain, nausea, vomiting, diarrhea or constipation, and/or gas. You may report side effects to FDA at 1-800-FDA-1088. Aug 17, 2023 · Diclofenac / misoprostol Pregnancy Warnings. Common side effects of diclofenac, lidocaine, and menthol topical may include: pain, burning, irritation, or skin changes where the medicine was applied You should not take Diclofenac Sodium Injection during the last 3 months of pregnancy as it may cause harmful effects on your baby. Peeling and Dryness: Prolonged or excessive gel use may lead to dryness, peeling, or changes in skin texture at the application site. Learn about dosage, side effects, uses and more. Next article in issue. The information within Common side effects may include: abnormal vaginal bleeding; heartburn, indigestion stomach pain, gas; nausea, vomiting; diarrhea, constipation; or. Hence, it is advised to avoid using Diclofenac Sodium Injection during the first 6 months of pregnancy also. Serious side effects may be more likely in older adults. Orthopedic Doctor. You could have more side effects. Ask a doctor if it is safe to breastfeed while using this medicine. NSAIDs like diclofenac topical patch may affect egg release (ovulation) in women. Consult your doctor Diclofenac is used to reduce pain, swelling, and joint stiffness from arthritis. It may not be safe to breastfeed while using this medicine. Diclofenac may interfere with Diclofenac and Misoprostol. Apr 28, 2022 · The present study examined the effect of DS exposure on median nerve development in rats during prenatal life. This medicine does not cure arthritis and will only help you as long as you continue to 4. Previous article in issue. For information about cardiovascular and gastrointestinal side-effects, and a possible exacerbation of symptoms in asthma, see Non-steroidal anti-inflammatory drugs Feb 24, 2021 · 50 mg enteric-tablet is. If you are able to become pregnant, your healthcare provider should do a pregnancy test before you start treatment with diclofenac sodium and misoprostol delayed-release tablets. Diclofenac Potassium Tablets contain. Jul 17, 2023 · This document does not contain all possible side effects and others may occur. Using an NSAID during the last 20 weeks of pregnancy can cause serious heart or kidney problems in the unborn baby and possible complications with your pregnancy. Diclofenac Mylan is a drug that inhibits inflammation, relieves pain, and lowers fever by affecting the production of prostaglandins in the body. Adult: Use the lowest effective dose for the shortest duration needed to achieve response. Some rare and very rare side effects might be serious. May 28, 2024 · low red blood cells (anemia) - pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet. Use of Diclofenac Sodium Injection can also lead to reduced labor (premature delivery). Avoid use in third trimester. Based on the studies reviewed, it is not known if tramadol can cause other pregnancy-related problems, such as preterm delivery (birth before week 37) or low birth weight (weighing less than 5 pounds, 8 ounces [2500 grams] at birth). Pre-operative and post-operative prevention of cystoid macular edema (CME) associated with lens extraction & intraocular lens implantation. Other common side effects of oral diclofenac include: Headache. Diclofenac 75 MG Injection is a painkiller used to relieve pain and swelling associated with osteoarthritis (tender and painful joints due to wear down of protective cartilage between the ends of the bones), rheumatoid arthritis (a type of arthritis affecting the small joints of the body), ankylosing spondylitis (pain and stiffness of bones of the spine), low back pain, neck pain, etc. Check with your physician for additional information about side effects. Tell your doctor if you are pregnant or plan to become pregnant. Know Diclofenac 50 MG Tablet uses, side-effects, composition, substitutes, drug interactions, precautions, dosage, warnings only on Lybrate. 2-6 Examples of prescription NSAIDs include ibuprofen, naproxen, diclofenac, and celecoxib. Diclofenac is a widely used analgesic so that exposure during pregnancy may frequently occur. Diclofenac is believed to work by decreasing the production of prostaglandins, like other drugs in this class. numbness of the feet, hands, and around the mouth. Diclofenac sodium is a phenylacetic acid derivative that is a white to off-white, virtually odorless, crystalline powder. pain or burning in the throat. The nature and extent of these findings were to find out what concentration causes embryo death. This is more likely in people who already have heart disease. If symptoms persist after 2 hours, may give additional dose of 50 mg. Diclofenac and pregnancy may not be an issue, except during the last trimester. Dec 9, 2022 · Diclofenac is a generic prescription medicine used to treat symptoms of certain types of arthritis in adults. signs of stomach bleeding --bloody or tarry stools Stop taking diclofenac and get medical help right away if you notice any of these rare but serious side effects: stomach/abdominal pain that doesn't go away, black/tarry stools, vomit that looks Feb 16, 2024 · You could have more side effects. Apr 1, 2024 · This medicine may raise your risk of having a heart attack or stroke. Post-operative inflammation after cataract surgery and other ocular surgical procedures. Specific data on diclofenac are rare. Do not apply more than 16 grams each day to any one of your affected feet, ankles, or knees. Taking a NSAID during the last 20 weeks of pregnancy can cause serious heart or kidney problems in the unborn baby and possible complications with your Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) used to treat acute and chronic pain (including dysmenorrhoea), and in the management of rheumatoid arthritis. Cardiovascular. If you have taken diclofenac and notice any adverse effects, the best thing to do is to see a gynecologist or obstetrician for Aug 23, 2023 · Diclofenac can affect ovulation and it may be harder to get pregnant while you are using this medicine. NSAIDs like diclofenac gel (1%) may affect egg release (ovulation) in women. Buying Diclofenac online offers convenience and accessibility, allowing you to purchase the medication Jan 27, 2021 · Diclofenac and Pregnancy. Frequency not reported: Ventricular septal birth defects . Am J Serious side effects may include heart disease, stroke, kidney problems, and stomach ulceration. Jan 27, 2023 · A double-blind randomized study of fetal side effects during and after the short-term maternal administration of indomethacin, sulindac, and nimesulide for the treatment of preterm labor. diclofenac sodium. It is This medication is a combination of 2 drugs: diclofenac and misoprostol. Apply diclofenac sodium topical gel 4 times a day (a total of 16 grams each day). Serious side effects of the Diclofenac/Misoprostol include: severe ongoing stomach discomfort or diarrhea, feeling very thirsty or hot, unable to urinate, heavy sweating, and. Jul 15, 2023 · Taking diclofenac during pregnancy can cause side effects such as persistent pulmonary hypertension (PPHN) and sudden closure of the ductus arteriosus—a blood vessel that directs blood away from the lungs in fetuses. If still needed, give 50 mg 4-6 hourly. NSAIDs like Diclozor (diclofenac gel (1%)) may affect egg release (ovulation) in women. Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) used to treat mild-to-moderate pain, and helps to relieve symptoms of arthritis (eg, osteoarthritis or rheumatoid arthritis), such as inflammation, swelling, stiffness, and joint pain. Taking a NSAID during the last 20 weeks of pregnancy can cause serious heart or kidney problems in the unborn baby and possible complications with your pregnancy. Learn about side effects, warnings, dosage, and more. . Learn more about diclofenac (Voltaren) at In relation to vaginal bleeding and postpartum haemorrhage, there was some association with diclofenac use towards the end of pregnancy. Risk Summary: Administration of misoprostol to pregnant women can lead to abortion, premature birth, or birth defects. Use of NSAIDs in pregnancy has been associated with an increased risk of miscarriage, persistent pulmonary hypertension of the newborn (PPHN), oligohydramnios, premature Diclofenac capsules (Zipsor, Zorvolex) and tablets (Cataflam) are used to relieve mild to moderate pain. Common Flector side effects may include: heartburn, gas, stomach pain, nausea, vomiting; diarrhea, constipation; or. Talk with your doctor. Serious cardiac side effects can occur in response to long-term use of Diclofenac. g. Flector Patch (diclofenac epolamine) is a pain medication used to treat Arthritis Pain, Acute Pain, Osteoarthritis, and Actinic Keratosis. Cataflam is not approved for use by anyone younger than 18 years old. See NSAIDs in Pregnancy in Non-steroidal anti-inflammatory drugs for further details. Diclofenac topical (for the skin) is used in adults to treat joint pain caused by osteoarthritis. dizziness. May 28, 2024 · Taking diclofenac during the last 3 months of pregnancy may harm the unborn baby. The FDA warns that NSAIDs like diclofenac (Flector, Cambia, Zorvolex) should be avoided in late pregnancy because it may cause serious cardiovascular complications. As diclofenac K conventional tab or cap: Initially, 50 mg at the 1st signs of attack. Feeling very tired or weak. Dynapar Tablet also provides effective relief from pain, stiffness, and swelling due to ankylosing spondylitis (pain due to fusing of bones in the spine), osteoarthritis (pain on movement due to wearing Tell your healthcare provider if you become pregnant or think you may be pregnant during treatment with diclofenac sodium and misoprostol delayed-release tablets. The most commonly reported side effects were burning, crusting, allergic contact dermatitis, pruritus, scarring, rash, soreness, and ulceration. It is likely safe during breastfeeding. Avoid use in first and second trimesters unless essential; the MHRA advises additional antenatal monitoring may be required if treatment is considered necessary by a doctor from week 20 of pregnancy onwards. Misoprostol may cause loss of pregnancy Voltaren (diclofenac) is a nonsteroidal anti-inflammatory drug (NSAID) used to treat inflammation and pain caused by rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, tendinitis, bursitis, and menstrual cramps. [[7], [8]]). Stop taking diclofenac and get medical help right away if you notice any of these rare but serious side effects: stomach/abdominal pain that doesn't go away, black/tarry stools, vomit that looks Most of the time, this reaction has signs like fever, rash, or swollen glands with problems in body organs like the liver, kidney, blood, heart, muscles and joints, or lungs. mild itching, burning, redness, or other skin irritation where the patch was worn. However, mammary transfer of drugs administered to mothers to breastfeeding infants remains a pressing concern. Call your doctor for medical advice about side effects. Diclofenac 50 MG Tablet is used for Rheumatoid Arthritis, Osteoarthritis, Ankylosing Spondylitis etc. This is not a complete list of side effects and others may occur. Administer one packet (50 mg dose) of Cambia for the acute treatment of migraine. Common side effects of diclofenac and menthol topical may include: skin dryness, redness, itching, or rash; blistering or hardening of the treated skin; While the exact effect of diclofenac on pregnancy is not fully understood, studies have suggested that it may increase the risk of miscarriage, birth defects, and other complications. This is not a complete list of side effects and For diclofenac potassium. Â. Skin reactions such as rash, itching, hives. It was determined whether it has any potential side effect when used during pregnancy. If you are 65 or older, use this drug with care. NSAIDs, including diclofenac, can increase the risk of complications such as high blood pressure, preeclampsia, and reduced kidney function. Empty the contents of one packet into a cup containing 1 to 2 ounces (30 to 60 mL) of water Using an NSAID (diclofenac) during the last 20 weeks of pregnancy can cause serious heart or kidney problems in the unborn baby and possible complications with your pregnancy. Sep 19, 2023 · Diclofenac Sodium ophthalmic preparation is used for- Inhibition of miosis during cataract surgery. nosebleed. Each mL of aqueous solution contains 37. General. Diclofenac extended-release tablets (Voltaren XR), tablets (Cataflam), and delayed-release tablets (available generically) are used to relieve pain, tenderness, swelling, and stiffness caused by osteoarthritis (arthritis caused by a breakdown of the lining of the joints), and rheumatoid Stop taking diclofenac and get medical help right away if you notice any of these rare but serious side effects: stomach/abdominal pain that doesn't go away, black/tarry stools, vomit that looks Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) used for the relief of pain, swelling, and joint stiffness caused by conditions such as arthritis. Stop taking diclofenac and get medical help right away if you notice any of these rare but serious side effects: stomach/abdominal pain that doesn't go away, black/tarry stools, vomit that looks Dec 25, 2023 · Another potential risk of using diclofenac during pregnancy is its effect on maternal health. This goes back to normal when Diclozor (diclofenac gel (1%)) is stopped. Different parameters were examined to evaluate its Using this medicine during the later part of pregnancy can harm your unborn baby. Feb 26, 2024 · Administration of nonsteroidal anti-inflammatory drugs (NSAIDs) during the third trimester of pregnancy may cause significant adverse effects, including premature closure of the fetal ductus arteriosus, pulmonary hypertension, fetal renal impairment, oligohydramnios, and inhibition of platelet aggregation. This medicine may raise the chance of severe and sometimes deadly stomach or bowel You may report side effects to FDA at 1-800-FDA-1088. Diclofenac 50 MG Tablet may be used to treat mild to moderate pain associated with muscle spasms, low back pain, neck pain, headache, tendonitis (swelling and pain of the connective tissue of bones and muscles), bursitis Sep 22, 2023 · Maximum doses: diclofenac 225 mg/day; misoprostol 200 mcg/dose and 800 mcg/day Comments:-For patients who experience intolerance, diclofenac 75 mg-misoprostol 200 mcg or diclofenac 50 mg-misoprostol 200 mcg orally twice a day may be used, however these regimens are less effective in preventing ulcers. The most common side effects are: stomach pain, diarrhea, dyspepsia, nausea, and. redness or other discoloration of the skin. 150 mmol (5. You should not take Diclofenac Sodium Injection during the last 3 months of pregnancy as it may cause harmful effects on your baby. The consumption of alcohol is not advisable as it may cause dizziness and in severe cases gastrointestinal bleeding. May 5, 2022 · Find everything you need to know about diclofenac (Voltaren), including what it is used for, warnings, reviews, side effects, and interactions. Jun 27, 2023 · NSAID (non-steroidal anti-inflammatory) medicines such as ibuprofen, naproxen, and diclofenac are well established medicines for short-term pain relief, but all NSAIDs have recognised side effects Pennsaid (diclofenac sodium) is a topical non-steroidal anti-inflammatory drug (NSAID) used to treat the symptoms of Acute Pain, Arthritis Pain, Actinic Keratosis, and Osteoarthritis. Post-traumatic inflammation in penetrating and non- penetrating Feb 9, 2024 · The dose for your feet, ankles , or knees is 4 grams of diclofenac sodium topical gel each time you apply it. Diclofenac may cause redness, soreness, scaling, and peeling of the affected skin. Diclofenac topical symptoms last for more than 7 days, or improve but come back after 3 days; or. Diarrhea and stomach/abdominal pain may occur within a few weeks after you start taking this medication, and Descriptions. This is not a complete list of side effects and other serious side effects or health Jan 27, 2024 · If you are 65 or older, use diclofenac topical patch with care. Common side effects may include: skin redness, numbness or tingly feeling, itching, dryness, scaling, or peeling where the medicine was applied. NSAIDs like this medicine (diclofenac capsules) may affect egg release (ovulation) in women. Feb 11, 2024 · If you are 65 or older, use Diclozor (diclofenac gel (1%)) with care. Use is not recommended in the third trimester of pregnancy. 5 mg of diclofenac sodium (34. Heart attack: dizziness, tiredness, cold sweat, trouble breathing, chest pain or tightness, anxiety. Pregnant female rats were divided into three groups: a control group, a saline group What are the side effects of Diclofenac Topical System (Patch)(Topical)? Uses, Warnings, Side Effects, Pregnancy, Interactions, Dosage, Overdose, and Images sections. Nov 21, 2023 · Diclofenac can affect ovulation and it may be harder to get pregnant while you are using this medicine. Although serious CV events can occur without warning symptoms, patients should be alert for the signs and symptoms of chest pain, shortness of breath, weakness, slurring of speech, and Stop using diclofenac and get medical help right away if you notice any of the following rare but very serious side effects: stomach/abdominal pain that doesn't go away, black/bloody stools, vomit Jun 13, 2023 · longer or heavier menstrual periods. Chest pain or pressure or a fast heartbeat . These complications can negatively impact both the mother and the fetus. People who use this medicine for a long time might also have a higher risk. Dizziness. Arthrotec has the side effects of diclofenac and misoprostol. If you are pregnant, you should not take Voltaren unless your doctor tells you to. What Diclofenac Mylan is and what it is used for. If you think you have become pregnant while using the medicine, tell your doctor right away. Dec 1, 2000 · A developing embryo is exposed to side effects of diclofenac sodium (DS), a commonly used non-steroidal anti-infl ammatory drug, since women may incidentally become pregnant while receiving DS Prescription NSAIDs and the risk of miscarriage in the first half of pregnancy. possible side effects. Therefore, it is important to consult with a healthcare professional before using diclofenac or any other medication during pregnancy. This may lead to systemic side effects like oral NSAIDs, such as stomach ulcers, kidney problems, and increased blood pressure. Nonsteroidal anti-inflammatory drugs (NSAIDs) use in pregnant women at 30 weeks gestation and later may cause premature closure of the fetal ductus arteriosus; NSAID use at 20 weeks This medicine contains less than 1mmol sodium (23mg) per 25 mg or 50 mg tablet, that is to say essentially ‘sodium-free’. Dosage for Cambia. Topical application of large amounts of diclofenac can result in systemic effects. Diclofenac / fluorouracil topical Side Effects. Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight. This medicinal product has 0. May 1, 2010 · The use of non-steroidal anti-inflammatory drugs like diclofenac in the third trimester of pregnancy can cause severe side effects, in particular oligohydramnios, premature closure of ductus Dec 21, 2023 · If you are pregnant, you should not use Diclona unless your doctor tells you to. One study did not find an increased chance for preterm delivery with tramadol use. lower back or side pain. This goes back to normal when diclofenac topical patch is stopped. Contact your healthcare provider immediately if you experience any of the following. Ask your doctor about any risk. [[4], [5], [6]]) and nephrotoxicity (e. Prostaglandins can cause inflammation, pain, and fever. seeing double. Mild to moderate pain. pale, gray, or blue colored skin, headache, rapid heart rate, shortness of breath, feeling light-headed, or tired. This goes back to normal when diclofenac gel (1%) is stopped. Like all medicines, Diclofenac Gel can cause side effects, although not everybody gets them. This drug may raise the risk of heart and blood vessel problems like heart attack and stroke. 6. This medicine may cause bleeding in your stomach or intestines. Such effects include increased pulse, arrthymias, chest pains, and tightening of chest. However, many people have no side effects or only have minor side effects. This may cause you to not be able to get pregnant. Moreover, it may show injection site pain and redness in case an injection form is given. It is used to reduce pain due to various conditions such as headache, toothache, backache, menstrual pain, sprains, and strains. This is a prescription drug and has some severe side effects such as abdominal pain, constipation, Diarrhoea, Nausea, and vomiting, these side effects can generally be avoided by taking the drug with food. 075 mmol (2. Oct 26, 2021 · It is also used in combination with other medications to treat the pain and swelling symptoms. Nov 1, 2010 · Conclusion. This goes back to normal when this medicine (diclofenac capsules) is stopped. Diclofenac 50 MG Tablet is used to relieve excessive pain and cramps associated with menstruation. Jul 18, 2023 · Serious Side Effects. Diclofenac potassium tablets, like other NSAIDs, may cause serious CV side effects, such as MI or stroke, which may result in hospitalization and even death. Acute migraine attacks. 1. This is not a complete list of side Oct 2, 2020 · Diclofenac (Solaraze, Voltaren) topical gel is a prescription medication used to treat osteoarthritis pain and actinic keratoses. Most publications What are some other side effects of this drug? All drugs may cause side effects. Diclofenac Mylan belongs to a group of Apr 15, 2024 · If you are 65 or older, use diclofenac gel (1%) with care. Apr 1, 2018 · Diclofenac like other NSAIDs can result in fetotoxic effects by reducing the fetal prostaglandin levels and therefore should be avoided in the third trimester. Using an NSAID (diclofenac) during the last 20 weeks of pregnancy can cause serious heart or kidney problems in the unborn baby and possible complications with your pregnancy. Our study suggests that the use of diclofenac is relatively safe during the first trimester of pregnancy and the studied sample size makes it possible to exclude a risk of congenital malformation higher than 3. Common side effects of Voltaren include stomach ulceration and bleeding, abdominal burning, pain, cramping, nausea, gastritis, and fluid retention. DYLOJECT (diclofenac sodium) Injection is a nonsteroidal anti-inflammatory drug for intravenous administration. Do not take this medication if you are pregnant or think that you may be pregnant. Rare side effects of the Diclofenac/Misoprostol include: none. wa hd uq ci bq yf kh hy nb zb